Beth Ahner, Ph.D., MIT, 1994. Trace metal speciation and trace metal detoxification mechanisms in marine microbes and plants. Dupont, C. L., R. K. Nelson, S. Bashir, J. W. Moffett, and B. A. Ahner. Novel copper-binding and nitrogen-rich thiols produced and exuded by Emiliania huxleyi. Limnology and Oceanography 49:1754-1762 (2004).
Ludmilla Aristilde, Ph.D., University of California-Berkeley, 2008. The research in my group focuses on investigating mechanisms underlying the environmental chemistry and/or environmental toxicology of emerging organic contaminants (antibiotics, pesticides, hormones) and biomacromolecules (enzymes and genetic elements).
Antje Baeumner, Ph.D. (Technical Biochemistry) Universität Stuttgart, 1997. Research interests focus on biosensor and lab-on-a-chip development for the detection of pathogens and toxins. A.J. Baeumner, J. Pretz, S. Fang “A Universal Nucleic Acid Sequence Biosensor with Nanomolar Detection Limits”, Analytical Chemistry, vol. 76 (4), pp. 888 – 894 (2004).
Klaus W. Beyenbach, Ph.D., Washington State University. Membrane transport of xenobiotics; organic cation and anion transport in the kidney; epitheliac transport mechanism. Beyenbach, K.W., and H. Wieczorek. The V-type H+ Atpase: Molecular Structure and Function, Physiological Roles and Regulation. J. Exp. Biol. 209: 577-589, 2006.
Stephen E. Bloom, Ph.D., Pennsylvania State, 1968. Mechanisms of lymphoid-cell sensitivity to drugs and environmental toxicants; in vitro model systems; apoptosis and cell cycle regulatory mechanisms. Muscarella, D.E., K.A. O’ Brien, A.T. Lemley, and S.E. Bloom. “Reversal of Bcl-2-mediated resistance of the EW36 human B-cell lymphoma cell line to arsenite- and pesticide-induced apoptosis by PK11195, a ligand of the m-benzodiazepine receptor” Toxicological Sciences 74:66-73, (2003).
Kathryn J. Boor, Ph.D., California, Davis, 1994. Bacterial responses to environmental challenges; food microbiology; food safety. Kim, H., H. Marquis, and K. J. Boor. “Sigma B contributes to Listeria monocytogenes invasion by controlling expression of inlA and inlB”. Microbiol. (in press 2005).
Paul R. Bowser, Ph.D. (Fish Pathology), Auburn University, 1978. Evaluation of therapeutic Compounds for treatment of diseases of fish; pathogenesis of tumors in fish caused by retroviruses. Tort, M.J., C. Jennings-Bayshore, D. Wilson, G.A. Wooster and P.R. Bowser. “Assessing the effects of increasing hydrogen peroxide dosage on rainbow trout(Onchorhynchus mykiss) gills utilizing a digitized scoring methodology”. Journal of Aquatic Animal Health. 14:95-103, ( 2002).
Dan L. Brown, Ph.D., Cornell, 1981. Nutritional toxicology; effects of naturally occurring feed toxicants on animal metabolism; poisonous plants. Boyer, J. D., D. C. Breeden and D. L. Brown. “Acer Rubrum toxicity in the horse: Isolation, identification and characterization of the oxidant compounds”. American Journal of Veterinary Research. (2002).
James W. Casey, Ph.D., Chicago, 1973. Viral oncogenesis, retroviral and herpesviral host interactions that induce tumors in natural populations of aquatic animals. J. Virol. 8765-71, 1998, Virology 246-99, 1998.
Rodney R. Dietert, Ph.D.,Texas/Austin, 1977. Immunotoxicology; effects of nutrients and environmental chemicals on immune function and ontogeny of the immune system. Dietert, R.R., J-E. Lee, J. Olsen, K. Fitch and J.A., Marsh. “Developmental immunotoxicity of dexamethasone: comparison of fetal vs. adult exposures”. Toxicology, (2003).
Anthony G. Hay, Ph.D.(Soil Microbiology), California/Riverside, 1997. Work in my lab focuses on the ability of microorganisms to degrade xenobiotics. Interests include the molecular biology, biochemistry, and ecology of pollutant degradation. Junker, L.M. and A.G. Hay. Effects of Triclosan Incorporation into ABS Plastics on Biofilm Communities. Journal of Antimicrobial Chemotherapy. 53:989-996,. (2004).
Alan Hedge, Ph.D. (Psychology), University of Sheffield, U.K., 1979. Research and teaching activities focus on issues of work environment design and workplace ergonomics, especially as these affect the health, comfort and productivity of workers. Kline, A.A., Landers, A.J., Hedge, A., Lemley, A.T., Obendorf, S.K. and Dokuchayeva, “T.Surface chemical exposure levels within enclosed sprayer cabs using carbon bed air filtration systems”. American Society of Agricultural Engineering Journal, 19 (4) 397-403, (2003)
Leon Kochian, Ph.D.,University of California, Davis, 1983. Metal ion transport processes in plants, with a particular interest in the roles of ion transport processes in plant responses to environmental stresses, and mechanisms of heavy metal transport, resistance and hyperaccumulation. Papoyan A, and Kochian LV. “Identification of Thlaspi caerulescens genes that may be involved in heavy metal hyperaccumulation and tolerance: Characterization of a novel heavy metal transporting ATPase”. Plant Physiol 136: 3814-3823, (2004).
Ann T. Lemley, Ph.D.(Chemistry), Cornell, 1971. Advanced oxidation treatment of pesticide wastes, degradation of chemicals in soil/groundwater. Wang, Q. Scherer, E.and Lemley, A.T. Metribuzin “Degradation by Membrane Anodic Fenton Treatment and Its Interaction with Ferric Ion”. Env. Sci and Toxicol. 38:1221-1227, (2004).
Leonard W. Lion, Ph.D.,Stanford, 1980. Aquatic biogeohemistry, interfacial reactions of pollutant chemicals. Contaminant fate and transport in natural systems. Tungittiplakorn W., Cohen C., and Lion L.W., “Engineered polymeric nanoparticles for bioremediation of hydrophobic contaminants”. Environ. Sci. and Technol. 39:1354-1358, (2005).
Rui Hai Liu, Ph.D.,(Toxicology), Cornell, 1993. Diet and cancer, natural bioactive compounds and free radicals in aging and carcinogenesis, functional foods/nutraceuticals and herbal remedies for cancer and hepatitis. Boyer, J., Brown, D., and Liu, R.H. “In vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayer”. Nutritional Journal, 4:1, (2005).
Eugene L. Madsen, Ph.D.(Microbiology), Cornell, 1985. Biodegradation of environmental pollutants; biogeochemistry of field sites; molecular approaches to characterizing naturally occurring microbial communities; microbial ecology. Park, W. and E. L. Madsen. “Characterization of nah in Pseudomonas putida Cg1 and its role in bacterial survival in soil”. Appl. Microbiol. Biotechnol. 66:209-216, (2004).
Murray McBride, Ph.D. (Soil Chemistry), Michigan State University, 1974. Trace metal behavior in long-contaminated soils , metal speciation, and bioavailability of toxic metals to important field crops. Qureshi, S., B.K. Richards, A.G. Hay, C.C. Tsai, M.B. McBride, P. Baveye, and T.S. Steenhuis. “Effect of microbial activity on trace element release from sewage sludge”. Environmental Science and Technology, 37:3361-3366, (2003).
Charles C. McCormick, Ph.D.,North Carolina State, 1979. McCormick CC, Parker R., The cytotoxicity of vitamin E is both vitaminer- and cell-specific and involves a selectable trait. J Nutr 134:3335-3342, 2004
Motoko Mukai, D.V.M, Ph.D. (Toxicology), University of Illinois at Urbana-Champaign, 2006. My research group studies toxicological effects of chemical compounds found in food and water, especially in regards to endocrine disrupting compounds that are found in low concentrations but bioaccumulate/biomagnify in the environment. For current opportunities in the Mukai lab, visit http://foodscience.cals.cornell.edu/graduate/applying/current-opportunities.
Alexander Yu. Nikitin, M.D., Ph.D., Pathology, St. Petersburg, Russia, 1988. Mouse models of human cancer, advanced cancer traits in early neoplasia, stem cells and cancer, pathobiology of neoplasias of reproductive and endocrine systems, live imaging and rational targeting of cancer. Cancer Res., 63: 3459-3463, (2003) Cancer Res. 65: 787-796, (2005).
Bendicht U. Pauli, D.V.M., Bern, Switzerland, 1967. Cancer cell biology, cancer invasion, metastasis. Beckley, J.R., B.U. Pauli, and R.C. Elble. “Re-expression of detachment-inducible chloride channel mCLCA5 suppresses growth of metastatic breast cancer cells.” J. Biol. Chem. 279:41634-41641 (2004).
Ruth E. Richardson, Ph.D. (Civil & Environmental Engineering) 2001 University of California at Berkeley. Research interests: bioremediation; molecular bioindicators; microbial ecology; contaminant fate and transport. Recent pubs: Morris, RM, Sowell, S, Barofsky, S, Zinder, SH, and Richardson, RE. (2006). Transcription and mass-spectroscopic proteomic studies of electron transport oxidoreductases in Dehalococcoides ethenogenes. Environmental Microbiology 8 (9), 1499?1509 Rahm, BG, Morris, RM, and Richardson, RE. (2006). Temporal Expression of Respiratory Genes in an Enrichment Culture Containing Dehalococcoides ethenogenes. Applied and Environmental Microbiology 72(8): 5486?5491
Mark Roberson, Ph.D.,Nebraska-Lincoln, 1990. Molecular mechanisms of hormone action; cell-specific gene regulation and intracellular signal transduction cascades induced by heterotrimeric G-protein-coupled receptors; endocrine disruptors and mammalian reproductive system. Roberson, MS, S Meermann, MI Morasso, JM Mulvaney-Musa and T. Zhang. . “A role for homeobox protein Distal-less 3 in the transcriptional activation of the glycoprotein hormone a subunit gene in choriocarcinoma cells”. Journal of Biological Chemistry, 276: 10016-10024, (2001).
Eloy Rodriguez, PH.D. (Natural Products Chemistry and Chemical Biology) University of Texas, Austin, 1975. Natural Products Chemistry, Ecology, Chemical Toxicology and Biology of Natural venoms (polypeptides) and natural small molecules from plants and arthropods that inhibit cancer cells, are antidiabetic and kill bacteria. “Natural Aldehydes from the Fruit of Viburnum Opulus That Inhibit Helicobacter pylori and Gastric Cancer Cells. Maria Laux and E. Rodriguez. 2006. J. of Phytochemistry (in submission).
Jeffrey G. Scott, Ph.D.,California/Riverside, 1985. Molecular biology, genetics and evolution of insecticide resistance; pesticide metabolism; gene regulation; insecticide neurotoxicology. Gao, J. and Scott, J. G. “Role of the transcriptional repressor mdGfi-1 in CYP6D1v1-mediated insecticide resistance in the house fly, Musca domestica”. Insect Biochem. Molec. Biol. 36: 387-395 (2006).
Michael L. Shuler, Ph.D. (Chemical Engineering), Minnesota, 1973. Viravaidya, K. and M.L. Shuler. “Incorporation of 3T3-L1 Cells to Mimic Bioaccumulation in a Microscale Cell Culture Analog Device for Toxicity Studies”. Biotechnol. Prog. 20:590-597,( 2004).
David M. Soderlund, Ph.D.,California/Berkeley, 1976. Biochemical toxicology of insecticides; insecticide neurotoxicology. Soderlund, D. M., J. M. Clark, L. P. Sheets, L. S. Mullin, V. J. Piccirillo, D. Sargent, J. T. Stevens, and M. L. Weiner. “Mechanisms of pyrethroid neurotoxicity: implications for cumulative risk assessment”. Toxicology 171: 3-59, (2002).
Jery R. Stedinger, Ph.D., Harvard, 1977. Water resources management, risk analysis, and stochastic hydrology. “Fate and Transport model of Cryptosporidium parvum”.J. of Envir. Engin., 125 (4), 325, (1999).
Barbara J. Strupp, Ph.D.,Cornell University, 1982. Neurobehavioral teratology and toxicology; developmental toxicology; low-level lead exposure: determination of the cognitive processes affected; development of improved therapeutic intervention (chelating agents); elucidation of the underlying mechanism of action. Stangle, DE., Strawderman M, Smith D., Kuypers M, & Strupp BJ. “Repeated regimens of Succimer show different treatment efficacy in brain versus blood in a rodent model of childhood lead exposure”. Environmental Health Perspectives, 112:302-308, (2004, online Oct. 31, 2003).
Olena K. Vatamaniuk, Ph.D. Kyiv State University, Ukraine. Analysis of molecular mechanisms of heavy metal detoxification, with emphasis on transport processes across vacuolaer/lysosomal compartment of plants/animals, required for maintenance of heavy metal tolerance. Vatamaniuk, O.K., Bucher, E.A., Sundaram, M.V. and Rea, P.A., CeHMT-1, a putative phytochelatin transporter, is required for cadmium tolerance in Caenorhabditis elegans. J. Biol Chem, 280, 23684-23690, 2005.
David Weinstein, Ph.D., U of Tennessee/Oakridge National Laboratory. Weinstein, D.A., J. A. Laurence, W. A. Retzlaff, J. S. Kern, E. H. Lee, W. E. Hogsett, and J. Weber. “Predicting the effects of tropospheric ozone on regional productivity of ponderosa pine and white fir”. Forest Ecology and Management, 205:73-89, (2005).
Robert Weiss, Ph.D. (Molecular Virology), Baylor College of Medicine, 1997. Molecular mechanisms for the maintenance of genomic stability; cellular responses to genotoxic stress; mouse models for human cancer. Weiss, R. S., P. Leder, and C. Vaziri. “Critical role for mouse Hus1 in a S-phase DNA damage cell cycle checkpoint”. Mol. Cell. Biol. 23:791-803 (2003).
David B. Wilson, Ph.D.,Stanford, 1966. Protein Engineering, Prokaryotic Gene Regulation, Genomics of Cellulolytic Bacteria and Mechanism of action of cellulases and other plant cell wall degrading enzymes. Zhou, W., Irwin, D.C., Escovar-Kousen, J. and Wilson, D.B. “Kinetic studies of Thermobifida fusca Cel9A active site mutant enzymes”. Biochem. 43, 9655-9663 (2004).
Andrew Yen, Ph.D. (Biophysics), Cornell, 1976. Cancer cell and molecular biology; regulation of the cell cycle and differentiation by retinoids, carcinogens, oncogenes, and tumor suppressor genes.
Yen, A., Varvayanis, S., Smith. J.L., and Lamkin, T.J.: Retinoic Acid Induces Expression of SLP-76: Expression with c-FMS Enhances ERK Activation and Retinoic-Induced Differentiation/G0 Arrest of HL-60 Cells. Eur. J. Cell Biol. 85:117-132, 2006.
Lamkin, T.J., Chin, V., Varvayanis, S., Smith, J.L., Sramkoski, R.M., Jacobberger, J.W., and Yen, A.: Retinoic Acid-induced CD38 Expression in HL-60 Myeloblastic Leukemia Cells Regulates Cell Differentiation or Viability Depending on Expression Levels. J. Cell. Biochem. 97:1328-1338, 2006.
Lamkin, T.J., Chin, V., and Yen, A.: Atra Induces p62DOK1 And P56DOK2 Expression Which Enhances Induced Differentiation and G0 Arrest of HL-60 Leukemia Cells. Amer. J. Hematol. 81:603-615, 2006.
Reiterer, G. and Yen, A.: Inhibition of the Janus Kinase Family Increases ERK1/2 Phosphorylation and Cuases Endoreduplication. Cancer Res. 66:9083-9087, 2006.